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Angelo Santos, MD

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With nearly two decades of experience in vascular surgery, Dr. Angelo Santos is a founding partner of Dakota Vascular and a trusted specialist in complex vascular care. He combines advanced surgical expertise with a strong focus on individualized, patient-centered treatment.

A Leader in Vascular Innovation

Prior to co-founding Dakota Vascular, Dr. Santos served as department chair of a leading regional vascular program, where he helped shape modern vascular care practices and treatment standards. His clinical leadership and experience support a thoughtful, evidence-based approach to vascular treatment.

Dr. Santos emphasizes individualized care and minimally invasive solutions whenever appropriate, with a focus on effectiveness, safety, and long-term outcomes.

Expertise That Inspires Confidence

Dr. Santos treats a wide range of arterial and venous conditions and is experienced in advanced vascular procedures, including:

  • Aortic Stent Grafting
  • Peripheral Angiography
  • Lytic Therapy
  • Angioplasty
  • Carotid Stenting

These techniques allow for tailored treatment plans using minimally invasive and endovascular approaches when possible.

Patient-Centered Approach

Dr. Santos is known for attentive listening and clear communication. He ensures patients understand their diagnosis, treatment options, and next steps, creating care plans that align with each patient’s condition and goals.

Certifications & Academic Leadership

  • Board Certified in Vascular Surgery, General Surgery, and Surgical Critical Care by the American Board of Surgery
  • Clinical Associate Professor, University of South Dakota

Education & Training

  • Medical Degree: West Virginia University School of Medicine, Morgantown, WV
  • Residency: Hennepin County Medical Center, Minneapolis, MN
  • Critical Care Fellowship: University of Minnesota, Minneapolis, MN
  • Vascular Surgery Fellowship: Allegheny General Hospital, Pittsburgh, PA

Life Beyond Medicine

Outside the operating room, Dr. Santos and his wife, Laura, keep busy with their four active children. Together, they love exploring new places across the U.S. and internationally. “Traveling with my family is my favorite way to recharge. It reminds me why I work so hard—to ensure every patient gets more time and more adventures with their loved ones,” Dr. Santos shares.

Your Vascular Health is Our Priority

Choosing Dakota Vascular means receiving care from experienced vascular specialists committed to personalized, evidence-based treatment. Dr. Angelo Santos and the Dakota Vascular team focus on improving circulation, managing complex vascular conditions, and supporting long-term vascular health.

Schedule your consultation today to experience expert vascular care with a compassionate touch. Call Dakota Vascular at (605) 306-6100 or request an appointment online.

Your health. Our mission. Expert vascular care you can trust.

About Us

  • Patrick Kelly, MD
  • Angelo Santos, MD
  • Gregory Nissen, MD

About Us

Dakota Vascular is a physician-owned clinic with the Midwest’s premier specialists for treating arterial and venous disease. We are an equal opportunity employer.

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  • 3801 S Elmwood Ave
    Sioux Falls, SD 57105

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